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15th World Congress on Microbiology and Clinical Research, will be organized around the theme “New Insights and Clinical Advancements in Microbiology”
Microbiology Summit 2022 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Microbiology Summit 2022
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Antimicrobial resistance is one among the foremost serious global public health threats during this era. Antimicrobial resistance is when a microbe evolves to become more or completely resistant to antimicrobials which previously could treat it. Antimicrobials include antibiotics, which kill or inhibit the growth of bacteria and AMR occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections harder to treat and increasing the danger of disease spread, severe illness and death. As a result, the medicines become ineffective and infections continue to persist in the body, increasing the danger of spread to others. Antimicrobial resistance is increasing globally due to greater access to antibiotic drugs in developing countries.
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Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that targets the lower part of the respiratory tract and causes severe acute respiratory syndrome (SARS). Potential rapid human-to-human transmission has caused therapeutic challenges in treating a wide range of humans affected by corona virus all over the world. Signs and symptoms of COVID-19 may appear two to 14 days after exposure and therefore the common symptoms include fever, headache, tiredness, difficulty in breathings, loss of taste and smell, diarrhea. Preventive measures to reduce the chances of infection includes getting vaccinated, staying at home, wearing a mask in public, avoiding crowded places, keeping distance from others, ventilating indoor spaces, washing hands with soap and water, and avoiding touching the eyes, nose, or mouth with unwashed hands.
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Bacteriophage, which are also known as phage or bacterial virus, any group of viruses that infect bacteria. Bacteriophages were discovered independently by Frederick W. Twort and Félix d’Hérelle. Research on phages has significantly enhanced our understanding of molecular biology, the genomes of prokaryotic cells, and viral ecology. Phages and lysins offer a viable alternative to the declining utility of antibiotics during this post-antibiotic era. They also provide ideal teaching tools for genomics and bioinformatics. Before the discovery and widespread use of antibiotics, it had been suggested that bacterial infections might be prevented and/or treated by the administration of bacteriophages. Now that more and more bacteria have developed resistance to antibiotics, scientists around the globe have a renewed interests in phages.
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Microbes are among our planet's most ubiquitous organisms. They're present in every biosphere, including a number of the most extreme locations on Earth. Microbes, generally, possess genomes much smaller in size compared to plants and animals, which makes them ideal for genetic and physiological studies. Microbial genomes are widely variable and reflect the large diversity of bacteria, archaea and lower eukaryotes. Bacterial genomes usually contain one circular chromosome, but species with more than one chromosome, linear chromosomes and combinations of linear and circular chromosomes also exist. Molecular phylogenetics has revealed that each clade of bacteria with genome sizes under 2 Mb was derived from ancestors with much larger genomes, thus refuting the hypothesis that bacteria evolved by the successive doubling of small-genomed ancestors.
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Virology is the field of study concerned with the study of the biology of viruses and viral diseases, including the distribution, biochemistry, physiology, molecular biology, ecology, evolution, and clinical aspects of viruses. a significant branch of virology is virus classification. Viruses are often classified consistent with the host cell they infect animal viruses, plant viruses, fungal viruses, and bacteriophages. Another classification uses the geometrical shape of their capsid or the virus's structure. Viruses range in size from about 30 nm to about 450 nm, which suggests that most of them can't be seen with light microscopes. the shape and structure of viruses has been studied by electron microscopy, NMR spectroscopy, and X-ray crystallography. Bacteriophages, the viruses which infect bacteria, are often relatively easily grown as viral plaques on bacterial cultures.
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A virtual clinical trial includes patient assessment and data collection which doesn’t occur in traditional settings, such as a health centre or hospital, and are instead facilitated via remote interaction. VCTs also called remote or decentralized trials are relatively new. virtual monitoring through wearable technologies could also be a passive process, remote trials may require participants to play a lively role in their own data collection. Virtual trials confer additional benefits by facilitating recruitment across a greater geographic radius while retaining the investigative team at one site. The advantages of virtual trials include patient recruitment, engagement, retention, and data collection with favorable effects on trial duration and costs.
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Food microbiology is the study of microorganisms, both in food and used to produce food. This includes microorganisms that contaminate food, as well as those utilized in its production. Microorganisms are of great significance to foods for the subsequent reasons: microorganisms can cause spoilage of foods, microorganisms are used to manufacture a wide variety of food products, and microbial diseases can be transmitted by foods. Foods can be considered as a medium for microbial growth. Considering the vast array of sources, substances, and methods with which food is produced, practically all kinds of microbe could be a potential contaminant. Food safety is a major focus of food microbiology. Numerous agents of disease and pathogens are readily transmitted via food which incorporates bacteria and viruses. Microbial toxins are also possible contaminants of food. Microorganisms and their products can also be used to combat these pathogenic microbes.
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Environmental microbiology is the study of the composition and physiology of microbial communities within the environment. The environment in this case means the soil, water, air and sediments covering the earth and might also include the animals and plants that inhabit these areas. It also includes the study of microorganisms that exist in artificial environments like bioreactors. Microbial life plays a primary role in regulating biogeochemical systems in the environment, including a number of the most extreme, from frozen environments and acidic lakes to hydrothermal vents at the bottom of deepest oceans, and in human intestine. Microorganisms are cost effective agents for in-situ remediation of domestic, agricultural, and industrial wastes and subsurface pollution in soils, sediments and marine environments. The ability of every microorganism to degrade toxic waste depends on the nature of each contaminant.
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Microbial physiology has played a really important role in both fundamental research and in industrial applications of microorganisms. The classical approach in microbial physiology has been to analyze the role of individual components in the overall cell function. With the progress in molecular biology it's become possible to optimize industrial fermentations through introduction of directed genetic modification – an approach mentioned as metabolic engineering. Microbial metabolism is how a microbe obtains the energy and nutrients it needs to live and reproduce. Microbes use various types of metabolic strategies and species can often be differentiated from one another supported metabolic characteristics. The precise metabolic properties of a microbe are the main factors in determining that microbe's niche, and sometimes allow that microbe to be useful in industrial processes or liable for biogeochemical cycles.
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A microbiome is the community of micro-organisms living together in a particular habitat. Humans, animals and plants have their own unique microbiomes, but so do soils, oceans and even buildings. The microbiome consists of microbes that are both helpful and potentially harmful. Most are symbiotic and a few, in smaller numbers, are pathogenic. the sector of microbiome research has evolved rapidly over the past few decades and has become a subject of great scientific and public interest. Microbial communities have been defined as the collection of microorganisms living together. More specifically, microbial communities are defined as multi-species assemblages, in which microorganisms interact with one another in a contiguous environment. the sector of microbiome research has emerged from environmental microbiome research and provides an interdisciplinary platform for several fields, e.g., agriculture, food science, biotechnology, bioeconomy, mathematics, plant pathology, and particularly human medicine.
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The field of micro biotechnology involves methods and strategies for the production and use of prokaryotic and eukaryotic microorganisms and archaea for substance synthesis and the use of the microorganisms or their substances in applications in the fields of white, red and green biotechnology. Environmental pollution has increased in the past few decades due to increased human activities on energy reservoirs, unsafe agricultural practices and rapid industrialization. Amongst the pollutants that are of environmental and public health concerns due to their toxicities are: heavy metals, nuclear wastes, pesticides, greenhouse gases, and hydrocarbons. Bioremediation can either be carried out ex situ or in situ, depending on several factors. Generally, ex situ techniques apparently are more expensive compared to in situ techniques because of additional cost due to excavation.
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Aquatic Microbiology refers to the study of the microorganisms that live in water, or which can be transported from one habitat to another by water. The marine environment supplies many kinds of habitats that support life, and partially depends on the saltwater that is in the sea. Various microorganisms like bacteria, cyanobacteria, protozoa, algae, and tiny animals such as rotifers are found naturally in fresh and saltwater. These can be important in the food chain that forms the basis of life in the water. The higher salt concentration, higher pH, and lower nutrients, relative to freshwater, are lethal to many microorganisms.
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The extremobiosphere consists of a broad range of biomes that include hyperarid deserts, deep-sea sediments and permafrost soils, as well as acid and high-temperature environments. These extreme habitats are characterized by combinations of environmental variables such as anoxia, aridity, extreme temperatures, low concentrations of organic matter, high salinity, and intense irradiation. Extremophiles are organisms that have the ability to thrive in extreme environments such as hydrothermal vents. The extremophilic microbial diversity and their biotechnological potential use in agricultural and industrial applications are going to be a milestone for future needs. Extremophiles and their cell components are expected to play a crucial role in the chemical, food, pharmaceutical, paper and textile industries as well as environmental biotechnology.
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Infectious diseases are the diseases which are caused by bacteria, viruses, fungi or parasites. They're normally harmless or maybe helpful. But under certain conditions, some organisms may cause disease. Infections are often caused by a wide range of pathogens, most prominently bacteria and viruses and hosts can fight infections using their immune system. Infectious diseases are sometimes called contagious diseases when they are easily transmitted by contact with an ill person or their secretions. Indirect contact like airborne transmission, contaminated objects, food and drinking water, animal person contact, animal reservoirs, insect bites, and environmental reservoirs are another way infectious diseases are transmitted. COVID-19, Influenza, Hepatitis B, Malaria, Dengue and Tuberculosis fall under the category of most common infectious diseases.
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Pathogenesis is the process by which a disease or disorder develops. Pathogenesis can include factors which contribute not only to the onset of the disease or disorder, but also to its progression and maintenance. It occurs because of complex interactions between an infecting pathogen and the immune system. The interaction between infectious agents and the immune system can be divided into several discrete phases that vary depending on the perspective. For the pathogen, this involves inoculation into a receptive host milieu, successful initial infection of 'target' cells and replication in suitable host cells, and for the host, this series of events includes recognition of infection by sentinel host immune cells, amplification of innate immune response and, lastly, adaptive immune responses that eliminate the pathogen.
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